The Finley Lab investigates how cellular metabolic pathways regulate cell fate decisions in stem cells and cancer cells. We combine genetic and metabolomic approaches to investigate cell-type specific ...

Cell Metabolism, launched in January 2005 ... with an emphasis on understanding the molecular basis of how the body self-regulates in the face of change, and how disturbances in these balances ...

The cell can control a metabolic pathway by the presence or absence of a particular enzyme. The cell can also regulate the rate of reaction of key enzymes. Enzymes are able to bind to their ...

A recent Science study explored how intranuclear metabolic enzymes establish the link between locus-specific epigenetic reprogramming of T cells and nutrient availability. Persistent antigen ...

Mitochondria play a crucial role in cellular energy production, and their dysfunction has long been linked to metabolic ...

However, how birth-associated metabolic changes affect the fate of tissue stem ... Considering that glutamine metabolism also regulates the functions of tissue stem cells other than NSCs, our ...

Following digestion and absorption of dietary fat, TG and cholesterol are packaged to form chylomicrons in the epithelial cells of the intestines. Chylomicrons circulate through the intestinal ...

The liver and pancreas are the main actors in glucose metabolism, but not the only ones. Muscles, adipose tissue and the brain play different roles. However, the prize for the best new actor in ...

The results highlight an important physiological function of PGAM in the differentiation and suppressive activity of Treg cells by regulating serine synthesis. This role is proposed to intersect with ...

Cancer metabolism refers to ... biosynthetic intermediates needed for cell growth and proliferation. Aldolase A is one of the glycolytic enzymes that regulate cancer cell proliferation.