Researchers have succeeded in generating high-quality feline embryonic stem cells using sperm and eggs from testes and ovaries discarded during sterilization surgery.

Microglia come from mesoderm, a layer that forms things like blood and immune cells, while glioma cells are thought to come from ectoderm, a layer that forms brain and nerve cells. However ...

UCLA scientists have identified a potential new strategy for treating glioblastoma, the deadliest form of brain cancer, by reprogramming aggressive cancer cells into harmless ones.

Version of Record: This is the final version of the article. This study combines hESC engineering, differentiation, detailed gene expression, genome occupancy, and pathway modulation to elucidate the ...

Congenital heart disease results in babies being born with structural defects to their hearts. It is one of the most common kind of human birth defects, yet its genetic causes remain poorly understood ...

The 'gold standard' test of pluripotency, however, is the capacity to differentiate into cells from all three germ layers: endoderm, mesoderm and ectoderm. In mice, this is typically demonstrated ...

Cellular unjamming is the collective fluidization of cell motion and has been linked to many biological processes, including development, wound repair, and tumor growth. In tumor growth, the ...