This adds to the growing body of work, from mouse and fly models, implicating lipid metabolism in neurodegeneration, particularly AD,” Amita Sehgal, Perelman School of Medici ...

The management of Leishmania donova ni (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment ...

Each cell is then encapsulated in a lipid droplet, together with a barcoded ... At Aelian, human T cells are up and running, NK cells and macrophages will be next,” said Bürckstümmer.

Our more recent observations indicate that certain oxidized lipids themselves are also recognized and endocytized through macrophage receptors. We previously showed that the adduct formed by the ...

Adipocytes and macrophages jointly express two FABPs ... of lipids to specific compartments in the cell, such as to the lipid droplet for storage; to the endoplasmic reticulum for signalling ...

The study, led by Prof. Charlotte Scott and her team, was published in Immunity and identifies a key role for lipid-associated macrophages (LAMs) and LAM-like Kupffer cells (KCs) in promoting recovery ...

In AKI, immune cells known as macrophages produce lipid mediators (LMs), which are lipids with significant physiological ...

Further studies showed that CePA could improve the activation and infiltration of liver macrophages during ... HFCFG-induced MASH by regulating lipid droplet accumulation and lipid deposition ...