Accumulation of fat molecules is detrimental to the cell. Researchers from the Yong Loo Lin School of Medicine, National ...

This adds to the growing body of work, from mouse and fly models, implicating lipid metabolism in neurodegeneration, particularly AD,” Amita Sehgal, Perelman School of Medici ...

The management of Leishmania donova ni (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment ...

Adipocytes in the skin contain one large liquid droplet of fat molecules (or lipids), which can be released from the cell in response to various biological events. In the two mouse models of skin ...

Metabolic disorders such as iron overload, glycolysis, insulin resistance, lipid dysregulation, and glutaminolysis are found to induce liver senescence and ferroptosis, which are hot topics in the ...

revealed that adropin regulates the macrophage lipid metabolism via PPARγ, thereby promoting the repolarization of macrophages from M1 to M2 (64). 6.4 MPO-ANCA-related lung injury Myeloperoxidase (MPO ...

As a result, oxidized LDL is continuously taken up via these receptors, loading the macrophages with cholesterol. The lipid-engorged macrophages have a foamy appearance and are called 'foam cells ...

In this important study, the authors investigate the role of mycobacterial Wag31 in lipid and peptidoglycan biosynthesis. A detailed analysis of Wag31 domain architecture revealed a role in membrane ...

A speaker highlighted key advances in lipid treatment in 2024. Topics included triglyceride and lipoprotein(a) management as well as another setback to the “HDL hypothesis.” In 2024 ...