Is MYC stability altered at specific subcellular locales, or when in partnership with certain DNA, RNA or protein molecules, or as a mechanism to regulate function, or in response to becoming ...

Free F1000 Evaluation When Maralice Conacci-Sorrell joined Bob Eisenman’s lab at the Fred Hutchinson Cancer Research Center in Seattle, Washington, she started studying the transcription factor and ...

That's because mis-regulation of Myc proteins is a hallmark of cancer and ... N-Myc/Aurora-A interaction without inhibiting the enzyme function is therefore a significant observation," explained ...

Preventing the cell's protein factories from making the notorious cancer-causing protein MYC could stop out-of-control tumors.

Researchers at the University of California at San Francisco have identified an RNA-binding protein that increased the ...

Over the past two decades, the idea of targeting transcription factors to combat malignancies has turned into a clinical ...

We found that it functions in maintaining homeostasis ... which is another oncogene product. This protein can work together with mutant Myc to drive cancer, so the inflammasome's normal job ...

"We found that it functions in maintaining homeostasis ... which is another oncogene product. This protein can work together with mutant Myc to drive cancer, so the inflammasome's normal job ...