AT2 dysfunction underlies many lung diseases, including interstitial lung disease (ILD), in which some inherited forms result from the mislocalization of surfactant protein C (SFTPC) variants. Lung ...

Disorders of surfactant protein biology cause dysfunction of alveolar type 2 cells and can lead to interstitial lung disease. This study describes the development of genetically manipulable, mature ...

16 The vibrating membrane system used in the current study enhances the delivery of the surfactant to the infant’s respiratory system, without protein denaturation (which ... was not associated with ...

Lung cancer is a particularly challenging form of cancer. It often strikes unexpectedly and aggressively with little warning, ...

A disrupted protein degradation process in heart muscle cells can lead to a range of severe heart diseases. In the case of ...

Despite new medication, cystic fibrosis often leads to permanent lung damage. Working with an international team, researchers from the Technical University of Munich (TUM) have discovered that the ...

Surfactants are substances that help fluids spread. They naturally exist in the human lungs and when doctors treat lung diseases, they sometimes use "exogenous surfactants" (from external sources ...

Acute respiratory distress syndrome (ARDS) is present in >10% of all people admitted to critical care and is associated with severe morbidity and mortality. Despite more than half a century since its ...

Scroll through TikTok or Instagram and you’ll be inundated with protein-centric recipes. Maximizing protein is a huge trend right now on social media—and not just in the usual suspects ...

In new research published on Saturday researchers revealed how smoking inhibits the function of protective immune cells in the lung ... the lungs activated by a protein called MR1.