Next Gen Diagnostics Announces That the University of Pittsburgh Has Joined the NGD Consortium
CAMBRIDGE, MA AND PITTSBURGH, PA / ACCESSWIRE / 10, 2025 / Next Gen Diagnostics (NGD), a pioneer in the development of machine learning models for whol ...
C&EN21d
Development of a Scalable Stereoselective Synthesis of Selected Potent ROMK Inhibitors
Department of Chemical Synthesis, Biocon Bristol Myers Squibb R&D Centre, Biocon Park, Plot No. 2 & 3, Bommasandra–Jigani Link Road, Bangalore 560 099, India ...
The EMBO Journal23d
Micropeptide hSPAR regulates glutamine levels and suppresses mammary tumor growth via a TRIM21-P27KIP1-mTOR axis
Administration of hSPAR or hSPAR-C significantly impedes breast cancer cell proliferation and tumor growth in xenograft models. These findings define hSPAR as an intrinsic control factor for cellular ...
earth26d
First total synthesis of mushroom compound could transform medicine
A recent breakthrough by researchers from Shinshu University, Japan, is changing this landscape. The team has successfully achieved the first total synthesis of inaoside A, a natural compound found in ...
Phys.org29d
Researchers report the first-ever total synthesis of a promising mushroom-derived compound
"Although the α-D-ribofuranoside structure is frequently found in natural products, there have been fewer reports of the synthesis of α-D-ribofuranosides than of the β-anomers. Thus, the ...
C&EN1mon
Supramolecular Combination Chemotherapy: Directly Inducing Immunogenic Cell Death To Inhibit Tumor Metastasis via Host–Guest Interactions
Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing 100069, P. R. China Laboratory for Clinical Medicine, Capital Medical University, Beijing ...
Frontiers2y
Breaking down the cell wall: Still an attractive antibacterial strategy
The cell wall is essential for bacterial growth and virulence but ... Considering the key enzymes in PG synthesis, some potentially feasible candidates have been found to inhibit its synthesis (Figure ...
Frontiers3y
Two Amphioxus ApeC-Containing Proteins Bind to Microbes and Inhibit the TRAF6 Pathway
Both them can aggregate bacteria by using their ApeC domain to bind with the cell wall component peptidoglycan (PGN ... the first strand cDNA using PrimeScript first Strand cDNA Synthesis Kit (Takara) ...