These useful findings assigned a novel functional implication of histone acylation, crotonylation. Although the mechanistic insights have been provided in great detail regarding the role of the YEATS2 ...

The research could contribute to the development of more effective anti-aging treatments in the future. The body's aging process may be more resilient than previously thought, according to a new study ...

Department of Chemistry, King’s College London, Britannia House, 7 Trinity Street, London SE1 1DB, U.K.

It is a unique member of the plastic family as it can be broken down into its constituent units (or monomers) by PETases, which are enzymes that degrade PET. Until now, scientists have discovered ...

Fixing high liver enzymes generally means treating the underlying cause of the condition. This means there is no one treatment or lifestyle modification that can help lower your liver enzymes. There ...

The acyltransferase p300 act as “writer” to catalyze histone Kbhb modification, and HDAC1, HDAC2, HDAC3 and SIRT1, SIRT2, SIRT3 were reported to be the “erasers” enzymes that have been identified for ...

Understanding the molecular mechanisms and consequences of histone modification enzymes in cartilage development, homeostasis and pathology provides fundamental and precise perspectives to interpret ...