A detailed medical and family history can be particularly important in pointing to an underlying hereditary condition. In the absence of any family history of pheochromocytoma or paraganglioma ...

Sir Tony Blair’s message to the hereditary peers in the House of Lords was meant to be “thank you and goodbye”. But it didn’t quite go to plan. His Labour government was forced into a ...

Background Until recently, determining penetrance required large observational cohort studies. Data from the Exome Aggregate Consortium (ExAC) allows a Bayesian approach to calculate penetrance, in ...

Hereditary high cholesterol (FH) is the most common hereditary disease and, if left untreated, can lead to atherosclerosis, cardiovascular disease and, in the worst cases, blood clots. It is ...

Pheochromocytoma-paraganglioma (PPGL) syndromes are rapidly evolving entities in endocrinology and oncology. Discoveries over the last decade have significantly improved our understanding of the ...