Innovative muscle patches derived from stem cells demonstrate efficacy in heart repair, improving function in primates and a human patient, with trials ahead.

A new molecular imaging technique— 18 F-FAPI PET—can detect the first signs of tissue ... heart and pulmonary artery of patients decreased, suggesting the potential reversibility of fibroblast ...

F-FAPI PET -- can detect the first signs of tissue remodeling in patients with pulmonary arterial hypertension (PAH), providing physicians with an early marker for disease progression. This approach ...

Research suggests that estrogen can inhibit the activation of cardiac fibroblasts—cells that create and maintain connective tissue in the heart. Research suggests that estrogen can stimulate new ...

This phenomenon includes not only the replacement of the damaged tissue by a fibrotic scar produced ... in orchestrating the transdifferentiation of fibroblasts and ensuing fibrotic remodeling of the ...

Using human myocardial samples, the degree of tissue hypoxia ... in cardiac fibroblasts during prolonged hypoxia which may contribute to the pro-fibrotic nature of an ischaemic event. Targeting ...

Research suggests that estrogen can inhibit the activation of cardiac fibroblasts—cells that create and maintain connective tissue in the heart. Research suggests that estrogen can stimulate new blood ...

Idiopathic pulmonary fibrosis (IPF) is the most devastating interstitial lung disease (ILD), more deadly than most cancers, and death usually ensues 2–5 years after diagnosis due to respiratory ...

Understanding why newborns, but not adults, can regenerate the heart could lead to treatments that "reprogram" adult ...