The current target of gout treatment is to reduce levels down to 6 mg/dL or less. SEL-212 is based on a uricase enzyme (pegadricase) that breaks down uric acid in the blood combined with an immune ...

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Doctors have long believed that high levels of uric acid in the blood (a condition called hyperuricemia) were the main cause ...

A study showed that urine alkalization therapy reduces gout flares, improves kidney health, and enhances lipid profiles in ...

For patients with gout who cannot get ... of SEL-212 hitting the tougher target of a uric acid level of 1.5 mg/dL or lower for 80% of month six after starting treatment. A six-month extension ...