New research provides a potential explanation for why long-term sclerostin neutralization leads to continued bone mass gain, despite attenuation of its short-term effects on bone formation ...

represent two forms of pathologic scarring characterized by excessive extracellular matrix (ECM) accumulation, fibroblast proliferation, aberrant proteolysis, and secretion of pro-inflammatory ...

Peptides have gained significant attention in research due to their possible role in regulating various physiological ...

13 Oxytalan fibres are a member of the elastic fibre family of connective tissue. Their presence is characteristic of the earliest identifiable stage of elastogenesis indicating local extracellular ...

Before arriving at Janelia three years ago, Postdoctoral Scientist Antonio Fiore was designing and building optical ...

Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...

Laboratory for Research on the Structure of Matter (LRSM), University of Pennsylvania, Philadelphia, United States ...

These particles, called extracellular vesicles, are considered attractive vehicle models for new drug therapies. But until now, researchers haven't had the complete picture of how they work.

Researchers have developed a way of bioprinting tissues that change shape as a result of cell-generated forces, in the same way that it happens in biological tissues during organ development.

Although Steven Spielberg is often recognized as being one of the greatest filmmakers of all-time, he has made so many masterpieces over the course of several decades, and a few of his greatest ...

Explore the role of the extracellular matrix (ECM) in prostate cancer progression and discover natural therapies, including milk thistle, turmeric, and green tea, that target the tumor ...