Each DNA molecule has two strands held together by bonds between compounds on the strands, called base pairs ... the main source of new genes is gene duplication. When the body’s genome ...

One hundred and fifty three of the 230 genetic variants were demonstrated to be missense mutations (38). These can result in ... such as a deletion of 10 nucleotides in exon 8 and a duplication of 16 ...

Despite their disease relevance, a comprehensive overview of the pathogenic effects of UTR mutations ... PCR duplication of single-end raw fastq files (150bp) was first removed by nubeam-dedup (Dai & ...

While polyploidy provides genetic redundancy by allowing mutations without affecting ... and Susumu Ohno's neofunctionalization by gene duplication—are not mutually exclusive.

Evolution is traditionally associated with a process of increasing complexity and gaining new genes. However, the explosion of the genomic era shows that gene loss and simplification is a much more ...

A recent study at Earth-Life Science Institute (ELSI) at Institute of Science Tokyo has developed a theoretical model that uncovers the dual role of polyploidy—organisms carrying extra genome ...

Base editing utilizes enzymes to modify single amino acids at the most foundational unit of DNA, called a base.

Researchers in the group of Dr. Myriam Charpentier discovered a mutation in a gene in the legume Medicago truncatula that reprograms the signaling capacity of the plant so that it enhances ...