Ubiquitin-binding domains (UBDs) are modular elements that ... receptor trafficking, DNA damage responses and inflammatory pathways. UBD preferences for distinct ubiquitin chains of specific ...

For decades, lab-made antibodies have been used to support patients fighting specific diseases. These treatments have become ...

Recombinant antibodies are invented antibodies formed by using recombinant DNA technology. While traditional monoclonal ...

This important study demonstrates the potential of synthetic gene circuits to detect and target aberrant RAS activity in cancer cell lines. The circuit design is novel and the evidence supporting the ...

Mysterious Blobs Found inside Cells Are Rewriting the Story of How Life Works Tiny specks called biomolecular condensates are ...

CHD6 has poly(ADP-ribose)- and DNA-binding domains and regulates PARP1/2-trapping inhibitor sensitivity via abasic site repair Discovering molecular pathways that sensitize cells to poly(ADP ...

Further, one part of the GTPase domain, the COR domain, has no known small molecule binding sites where drugs could attach themselves. "This is a very understudied area," Xiong says. "There is not ...

Kuick Research Report Highlights Ongoing Developments In Molecular Switches Application Therapeutic Targets & Drug Delivery ...

Q4 2024 Earnings Call Transcript February 11, 2025 Arvinas, Inc. beats earnings expectations. Reported EPS is $-0.63, ...

On the basis of sequence conservation within structures, the whole sequence and four domains were used independently to create five features via BLAST. BindN was created according to the DNA-binding ...

Researchers from Southwest Jiaotong University published the discovery of novel high affinity peptides against the protein of human DNA binding domain of FOXM1 (FOXM1-DBD) to be developed for the ...

HURA READ THE FULL HURA RESEARCH REPORT We are initiating coverage of TuHURA Biosciences, Inc. (NASDAQ:HURA) with a valuation ...