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The peptides were synthesized with protease-resistant D-amino acids in reversed order to increase half-life and the HIV-TAT sequence was added to enhance cellular uptake. The most effective FOXM1 ...

Here we explore peptide inhibitors of Cdc20, a substrate-recognition subunit and activator of the E3 ubiquitin ligase the anaphase promoting complex/cyclosome (APC/C) that is essential in mitosis and ...

Collagen, the body's most abundant protein, has long been viewed as a predictable structural component of tissues. However, a ...

Researchers have used artificial intelligence to identify 25 new protein compounds that can kill bacteria and fungi, ...

Researchers at Rice University have developed a new method for performing chemical reactions using water instead of toxic ...

Scientists have developed a series of strategies, including modified block copolymers coupled with cell penetrating peptides that better assemble into micelles, form stable complexes with siRNA, or ...

Researchers from the Institute of Science Tokyo and Osaka Medical and Pharmaceutical University said that they have developed a peptide that can bind to the spike proteins of SARS-CoV-2 to prevent ...

Antimicrobial peptides (AMPs) are promising novel antibiotics since they have shown antimicrobial activity against a wide range of bacterial species, including multiresistant bacteria; however, ...

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