Cells navigating in complex microenvironments frequently encounter narrow spaces that physically challenge migration.

The management of Leishmania donova ni (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment ...

In this manuscript the authors established a novel three-dimensional culture system for stratified epithelia that allows epithelial cells to undergo epithelial-to-mesenchymal transition (EMT) and ...

Diagnostic markers are biological parameters that aid the diagnosis of diseases. Examples include the presence of particular genetic variants and the levels of particular proteins in body fluids.

Genetic markers are DNA sequences with known physical locations on chromosomes. They are points of variation that can be used to identify individuals or species, or may be used to associate an ...

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Collective migration plays critical roles in developmental, physiological and pathological processes, and requires a dynamic actomyosin network for cell shape change, cell adhesion and cell-cell ...

Introduction: While the prevalence of neurodegenerative diseases associated with dementia such as Alzheimer's disease (AD) increases, our knowledge on the underlying mechanisms, outcome predictors, or ...

The CDH1 promoter common polymorphism −60C/A and the CDH1 exon 4 mutation site were used as intragenic markers for LOH analysis in DNA extracted from tumour and normal material from the proband. DNA ...