Northwestern Medicine scientists have discovered new details about how the human genome produces instructions for creating proteins and cells, the building blocks of life, according to a pioneering ...

New research shows that a network of subcellular structures similar to those responsible for propagating molecular signals that make muscles contract are also responsible for transmitting signals in ...

Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...

Mitochondrial defects, however, are associated with the development of diseases such as type 2 diabetes. Patients who suffer from this disorder are unable to produce enough insulin or use the insulin ...

The new research reveals a novel mechanism for signal transmission in brain cells and helps answer an open question in neuroscience about how intracellular signals travel over long distances in ...

This influx of calcium at the contact site attracts and activates a kinase called CaMKII, a protein known to be important in ...

Mitochondria are essential for generating energy that fuels cells and helps them function. Mitochondria are essential for generating energy that fuels cells and helps them function.

In this manuscript the authors established a novel three-dimensional culture system for stratified epithelia that allows epithelial cells to undergo epithelial-to-mesenchymal transition (EMT) and ...

Every cell in the body normally has its fixed place as part of a tissue structure. Except for a few cell types, such as blood ...