The only mutation present in AML BM-MSC at serial time points of diagnosis, complete remission and relapse was a mutation in the PLEC gene encoding for cytoskeleton key player Plectin in one AML ...

Facundo’s lab studies B-cell biology and antibody responses, particularly B-cell receptor signaling dynamics, involvement of the cortical cytoskeleton, and more recently the role of B-cell metabolism.

This suggests that only insulin-recruitable transporters are affected by disruption of the actin cytoskeleton ... Brosius for the gift of the GLUT1 antibody, Dr. I. Hers (Department of ...

Gene ontology biological process analysis of ATAC sequencing data demonstrated key elements associated with phosphoinositide regulation, essential for cytoskeleton organization, chemotaxis and ...

Specifically, the developmentally essential, tissue-restricted TGFβ signaling pathway, regulates and is regulated by the MT cytoskeleton ... using standard procedures [30]. Primary antibodies used ...

Explore the role of the extracellular matrix (ECM) in prostate cancer progression and discover natural therapies, including milk thistle, turmeric, and green tea, that target the tumor ...

10 Detection of RhoA-GTP, S1P, total soluble collagen, and supernatant TGF-β1 Analysis of intracellular RhoA-GTP, S1P, soluble collagen and TGF-β1 was performed using a RhoA-GTP activity assay kit ...

No writing assistance was utilized in the production of this manuscript. Monoclonal antibodies are novel therapeutic agents used with great success in the treatment of rheumatoid arthritis (RA).

This study presents solid evidence for distinct neurotransmitter release modalities between two subclasses of dopaminergic neurons in the olfactory bulb, highlighting an important finding that ...

A thyroglobulin antibody (TgAb) test looks for certain antibodies that attack the thyroid. The presence of TbAb in high levels may indicate that someone has an autoimmune condition. To conduct a ...

Ideally, the immune system will produce long-lasting antibodies recognizing that specific virus, thereby providing protection. But Scripps Research scientists have now discovered that for some HIV ...

Ideally, the immune system will produce long-lasting antibodies recognizing that specific virus, thereby providing protection. Scientists at Scripps Research have now made a new discovery for some ...