Cowden disease and other rare, related disorders, such as Bannayan-Riley-Ruvalcaba, Proteus, and Proteus- like syndromes, are often caused by mutations of the PTEN gene. CONCLUSIONS: Because of ...

Cowden disease (CD) is a genetic disease associated with multiple hamartomas and malignant neoplasms. During investigations for possible subnormal fertility, a series of eight males with CD ...

Associated familial diseases have their own inheritance pattern, and some have known gene defects. They include familial medullary thyroid carcinoma (RET gene), familial adenomatous polyposis (APC ...

A team led by University of Pittsburgh School of Public Health geneticists has shown, for the first time, that a gene "silencer" that resides in junk DNA is directly sparing people from a devastating ...

Accumulation of clots causes some of the most severe symptoms of sickle cell disease, including strokes, kidney failure, ...

More than 1,000 genes may serve as possible treatment targets for individuals with kidney disease, according to a new study, ...

A new study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and ...

Tonight will trend colder as cloud breaks further and lengthy clear spells develop. Cloud thickening again towards the end of the night with a slight chance of a shower. Sunday Tomorrow will see ...

An international research team has identified key genetic factors that confer protective effects against Alzheimer's disease (AD) through a comprehensive genetic analysis of East Asian populations, ...

Stargardt disease also known as Stargardt macular degeneration, is commonly caused by changes in a gene, ABCA4. This gene influences how your body uses Vitamin A. There is currently no cure ...

A new study of nerve cells affected by Huntington’s disease (HD) reveals that the disease-causing gene slowly expands over time but doesn't start causing harm until it hits a toxic threshold ...