The functioning of the brain relies on the precise organization of neuronal connections. In an article published in ...

Laboratory for Research on the Structure of Matter (LRSM), University of Pennsylvania, Philadelphia, United States ...

elegantly show that, in Drosophila, astrocytes signal to neurons ... revealing distinct connectivity patterns in the hippocampus and motor cortex, and providing insights into astrocyte network ...

Working in Drosophila fruit flies, they showed that this could lead to microcephaly. ANKLE2 is known to be involved in brain development in the fetus, but is found in cells throughout the body.

With compelling electrophysiological and behavioural evidence, this work establishes that the activity of insulin-producing cells (IPCs) depends on the nutritional state in Drosophila and that, like ...