Monoallelic loss of PTEN and ARID1A is identified in normal colonic epithelium. The resulting haploinsufficient phenotypes ...
This valuable study presents a mouse gastruloid model that can be used to generate hematopoietic progenitors as well as leukemic cells. However, in its current form, the manuscript is inadequate ...
In this Review, the authors provide a comprehensive historical overview of the advancements in the understanding of biology and genetics of paediatric renal non-Wilms tumours, and discuss how this ...
Indeed, the microenvironment dictates the final effect of MSCs on target cells, as exemplified by the opposite outcomes that can arise from the interaction of MSCs with DCs and NK cells in the ...
NAINR. 2004;4(4):231-239. Acanthocyte Erythrocyte identified by numerous spiny cytoplasmic projections; similar to a Burr cell Acanthocytosis, condition in which the majority of erythrocytes are ...
The impact of gut microbial signals on hematopoietic stem cells and the bone marrow microenvironment
Recent evidence suggests that the gut microbiota influences HSCs differentiation by modulating the bone marrow microenvironment through microbial products. This paper comprehensively analyzes the ...
From the Center for Systems Biology (W.C.P., M.N., F.K.S.), Massachusetts General Hospital and Harvard Medical School, Boston. From the Center for Systems Biology (W ...
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