Myosin II plays the most important role in cellular force generation. Myosin II molecules self-assemble into filaments with different structures depending on myosin II isoforms and other conditions ...

A dysfunctional signaling pathway in the hippocampus has been linked to chronic pain-related memory impairment in mice.

The cytoskeleton is involved in all main functions of immune cells related to the response to infection. Studies of the cytoskeletal proteome can vastly contribute to our understanding of ...

The self-assembled polymer-based fibrous network mimicked the structure and function of a natural cytoskeleton. The coacervate platform was compatible with various artificial cell architectures ...

Every cell in the body normally has its fixed place as part of a tissue structure. Except for a few cell types, such as blood ...

Alushin's lab specializes in understanding the cytoskeleton—the network of protein filaments, including actin, that form a cell's infrastructure. Actin serves many functions: it provides cells ...

Filopodia help cells move but also aid cancer spread. Scientists have revealed how fascin proteins build these structures, ...

They are a major component of the cytoskeleton and mediate crucial cellular functions including formation of the mitotic spindle that segregates chromosomes during cell division and intracellular ...