Beta3-adrenergic receptors (β3AR) have emerged as significant players in the management of heart failure (HF) and cardiac function. Traditionally, beta-adrenergic receptors have been associated ...

Lopez-Sendon J, Swedberg K, McMurray J et al. Expert consensus document on β-adrenergic receptor blockers. Eur. Heart. J. 25(15), 1341–1362 (2004). Brodde OE. β-1 and β-2 adrenoceptor ...

Churchwell said the drug class slows the heart by inhibiting and binding to beta one and beta two receptors on the heart. They limit the production of epinephrine, norepinephrine, adrenaline and ...

Major beta blocker mortality trials in chronic heart failure: a critical review. Heart. 1999;82(suppl 4):IV14 IV22. Altered adrenergic receptor sensitivity due to polymorphic variation.

Beta-blockers antagonize beta-1 and beta-2 receptors which are the usual targets of the sympathetic nervous system, including epinephrine and norepinephrine. This results in a decreased heart rate ...

Basic science researchers at the Johns Hopkins University School of Medicine are advancing heart health research by finding ...

‘Inderal’) is a potent blocking agent for beta receptors, and it has been shown to block the action of isoprenaline in increasing the heart rate (J. Raventos, personal communication). In the ...

Beta-blockers are thought to cause “unopposed alpha receptor agonism.” Since the beta receptors would be occupied by the beta-blockers, substances (epinephrine, norepinephrine, etc.) ...