Functional subpopulations of β-cells emerge to control pulsative insulin secretion in the pancreatic islets of mice through calcium oscillations.

Mitochondrial defects, however, are associated with the development of diseases such as type 2 diabetes. Patients who suffer from this disorder are unable to produce enough insulin or use the insulin ...

Mitochondria are well known as the powerhouses of the cell. These crucial, energy generating organelles even have their own little genomes... | Cell And Molecular Biology ...

People with prediabetes often develop diabetes, but many of them manage to reverse to normoglycemia. What determines these ...

An innovative organoid model mirrors the pancreas' complexity, generating all three key cell types to explore development and ...

There isn't a cure for the condition, but doctors may recommend medications to slow down the progression of the disease or ...

Diabetes is a common, lifelong condition that occurs when the pancreas doesn't produce enough insulin, or when the body is unable to effectively use the insulin it produces ...

Our perspective about glucose toxicity as it pertains to the pancreatic ß-cell is that the characteristic decreases in insulin synthesis and secretion are caused by decreased insulin gene expression.

A revolutionary approach to immune therapy has emerged: engineered immune cells that protect healthy tissue without ...

Olive oil bioactives, including MUFAs, polyphenols, and triterpenoids, modulate gene expression linked to insulin sensitivity ...