EurekAlert!1mon
Research points the way to lifesaving antiparasitic drugs while unlocking a scientific mystery
The findings, reported in Nature Communications, also solve a decades-long scientific puzzle that’s prevented drugmakers from successfully using azole antifungal drugs to treat visceral ...
Nature1y
Fighting the rising tide of antifungal resistance: a global challenge
In 1981, the first azole antifungal, the diazole ketoconazole, was introduced to the market; then, in the early 1990s the first-generation triazoles, fluconazole and itraconazole, became available.
Pharmabiz9d
One Health: EU agencies unite to tackle azole fungicide resistance in Aspergillus fungi
EU agencies unite to tackle azole fungicide resistance in Aspergillus fungi: Amsterdam, The Netherlands Monday, February 3, 2025, 17:00 Hrs [IST] For the first time, t ...
Hosted on MSN1mon
Discovery of enzyme pathway may lead to lifesaving leishmaniasis treatments
The findings, reported in Nature Communications, also solve a decades-long scientific puzzle that's prevented drugmakers from successfully using azole antifungal drugs to treat visceral ...
Medscape5d
Mitigation of Human-Pathogenic Fungi That Exhibit Resistance to Medical Agents: Can Clinical Antifungal Stewardship Help?
fumigatus has important implications for the scope of clinical antifungal stewardship. Given the human health consequences of disease caused by azole-resistant Aspergillus, it is hardly surprising ...
Monthly Prescribing Reference1y
Alprazolam Intensol
Labor & delivery. Pregnancy (Cat.D), nursing mothers: not recommended. See Contraindications; other azole antifungals: not recommended. Potentiates CNS depression with alcohol, psychotropics ...
Medscape13y
Critical importance of Antifungal Dosing in Children
Fluconazole, a very safe and effective azole antifungal, requires a much higher dose in children (12 mg/kg/day) compared with adult patients. In addition, the neonatal field is exploring ...
Strong launch for Cresemba in Japan triggers first sales milestone payment from AKP to Basilea
The achievement of the first sales milestone already in the second year of commercialization is a testament of the commercial capability of our partner AKP in this important market. The strong sales ...
University of Bristol4y
Understanding agricultural azole use, impacts on local water bodies and AMR
While occurrence and risks of azole antifungals in wastewater and meat industry have been studied, their presence in surface water and potential threats to water quality are underexplored. This ...
Tahlequah Daily Press1d
EPA releases final risk evaluation on wood additives
Chromated arsenicals are a group of pesticides that protect wood against termites, fungi and other pests that can degrade or ...
Strong sales growth for Cresemba and Zevtera trigger further milestone payments to Basilea
For Cresemba, this comprises a milestone payment for sales in Canada, by AVIR Pharma Inc, as well as the first sales milestone payment for the Middle East and North Africa (MENA) region, by Hikma ...