A single gene in the shorebird species known as ruffs controls the levels of testosterone in males, and this in turn affects ...

Responses were similar among patients with estrogen patches and ARPIs compared to luteinizing hormone releasing hormone ...

Barry Goy, MD, provides insight into the clinical implications of a retrospective analysis examining 15-year outcomes in patients with intermediate-risk prostate cancer.

Quality of life, treatment impact and duration, and the importance of individualized therapy are at the center of ...

Oxytocin receptor (Oxtr) signaling influences complex social behaviors in diverse species, including social monogamy in prairie voles. How Oxtr regulates specific components of social attachment ...

Co. Ltd. has identified proteolysis targeting chimeras (PROTACs) comprising an E3 ubiquitin ligase binding moiety coupled to an androgen receptor targeting moiety through a linker acting as androgen ...

But of course, the last few years, really the last decade to decade and a half, has been the advent of what we call, now call ARPIs, or androgen receptor pathway inhibitors. And these are really ...

dDepartment of Molecular Brain Science, Graduate School of Medical Sciences, Kumamoto University, Kumamoto 860-8556, Japan eLaboratory for Molecular Mechanisms of Brain Development, RIKEN Center for ...

Want all the hottest music and gear news, reviews, deals, features and more, direct to your inbox? Sign up here. “The song was an expression of my tempestuous private life over the three years before.

Key contributors to PrCa progression include genetic mutations, elevated androgen receptor expression, gene amplification, and the rise of androgen receptor splice variants. Although androgen ...

It was not until later that it was discovered that androgen insensitivity was caused by mutations in the androgen receptor gene. The symptoms of androgen insensitivity depend on the type. Individuals ...

"We turned the results into a linear model that could estimate months of androgen exposure with surprising accuracy for both mice and sheep," Dr. Sugrue says. "Importantly, when we removed the ...