ANCA-Associated Vasculitis This includes granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), eosinophilic granulomatosis with polyangiitis (EGPA). This type of vasculitis ...
The antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) include granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA) and eosinophilic GPA (EGPA).1–3 AAV ...
Regional differences exist in the clinical presentation and treatment of ANCA-associated vasculitis across Europe ... Patients with newly diagnosed or relapsing granulomatosis with polyangiitis (GPA) ...
Although the organ involvement in this case is atypical, a granulomatosis with polyangiitis (GPA)-like syndrome was suspected. Systemic and topical ophthalmic steroids were initiated, with effective ...
Sixty-two (68%) patients were diagnosed with GPA, 19 (21%) with EGPA and 10 (11%) with MPA. ANCA was detectable in 88% of patients, with specificity against proteinase-3 being more frequent (64%) than ...
Rituximab, an anti‐CD20 B‐cell depleting chimeric monoclonal antibody, has proven efficacy for remission induction and maintenance in GPA and MPA.11–13 The rationale for rituximab in EGPA comes from ...
There is no guarantee that they will become commercially available for the use(s) under investigation. * Newly diagnosed or relapsed GPA and MPA (according to the 2022 ACR/EULAR classification ...
(4) ANCA positivity and optic nerve sheath or pachymeningeal enhancement on MRI aided in the discrimination of optic neuropathy associated with GPA from demyelinating optic neuritis. (5) Identifying ...
Contact the study team to discuss study eligibility and potential participation. Newly diagnosed or relapsed GPA and MPA (according to the 2022 ACR/EULAR classification criteria for GPA and MPA) ...
A significant percentage of patients with RA and ANCA positivity were also diagnosed with AAV, with GPA being the most common subtype.