HSF1 transiently accumulates in the nucleus of human monocytes undergoing macrophage differentiation, including M-CSF-treated peripheral blood monocytes and phorbol ester-treated THP1 cells.

In monocytes and other immune cells ... that investigating the metabolic profile of immune cells can allow inferences to be made about their differentiation state. In this study, chronological ...

For example, IL-4-based treatments could encourage differentiation of Ly6G + macrophages and subsequently boost progenitor cell proliferation and repair. “You have less control over that scenario, ...

we have investigated the developmental origin and homeostasis of macrophages and the related cell types monocytes and dendritic cells. These cells play a major role in diverse types of cancer and can ...