Rondo Therapeutics Presents Preclinical Data at ASCO GU for its Novel CD28 x Nectin-4 Costimulatory Bispecific Antibody for Advanced Bladder Cancer
Rondo Therapeutics, a privately held biopharmaceutical immuno-oncology company pioneering the development of next-generation ...
Nature23y
Adoptive tumor therapy with T lymphocytes enriched through an IFN-γ capture assay
anti-CD28 (37.51, both Pharmingen, San Diego, California); TIL-26: anti-CD3 (OKT3, 200 ng/ml Janssen-Cilag, Neuss, Germany) for 6 h or 4 h, respectively. Freshly prepared TILs from RCC were ...
Nature9y
CD28 deletion improves obesity-induced liver steatosis but increases adiposity in mice
The relationship between bacterial load and the pro/anti-inflammatory balance within AT will deserve further exploration. Cd28KO mice were protected against fat accumulation in the liver.