These findings provide a potential explanation for the evolution of the unique HIV capsid structure: its conical shape might be necessary to break the nuclear pore complex and to complete the ...

HIV-1, like other viruses ... Another important discovery was an intricate RNA structure near the critical "frameshift site" in the viral genome. This frameshift site is essential for the virus ...

When we know the structure of a protein, we can attempt to design small drug molecules to bind to it and block its function. The power of this approach has been shown in the battle against HIV and ...