The cytoskeleton of eukaryotic cells is made of filamentous proteins, and it provides mechanical support to the cell and its cytoplasmic constituents. All cytoskeletons consist of three major ...

Spectacular progress has been made in our understanding of the physical processes that underlie the functions and mechanisms of cytoskeletal proteins. For example, the atomic structures of actin ...

Actin proteins group together to form a network of thin filaments that spread throughout a cell. This actin network is dynamic, meaning that the filaments can either grow or shrink to fit the ...

Just like your body has a skeleton, every cell in your body has a skeleton—a cytoskeleton to be precise. This provides cells with mechanical resilience, as well as assisting with cell division.

Imaging the actin cytoskeleton in presynapses is not easy as the abundance ... Using a CRISPR-Cas9 system, they tagged endogenous actin to enhance its visibility in just a few cells of their ...

We aim to understand the molecular logic behind the dynamics of the actin cytoskeleton at endocytic sites and how disturbances in this process affect physiology and disease progression. Leonardo is ...

Our ultimate goal is to define if manipulating the cytoskeleton of cancer cells will lead to improved efficacy of therapeutic approaches in patients with metastatic disease, with a special focus on ...

In our lab, we aim to elucidate the interplay of clathrin structures with the actin cytoskeleton and cellular adhesions ... approach combining state-of-the-art techniques in cell biology, biochemistry ...