Figure 1: Recruitment of cyclin E/Cdk2/Xic1 and SCF to replication origins. The third role of cyclin E/Cdk2 in Xic1 degradation is the recruitment of SCF components to chromatin 1, which is likely ...
Recent work has discovered the role of the cyclin-dependent kinase (CDK)-binding ... CDKs and links Cks1 with the Skp2 subunit of the SCF ubiquitin ligase. The cell's ability to self-reproduce ...