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Study reveals evolution of human cold and menthol sensing protein, offers hope for future non-addictive pain therapies
"By understanding the evolutionary history of TRPM8, we hope to contribute to designing better drugs that offer relief without the dangerous side effects associated with current painkillers." ...
I’m a doctor — this simple trick will stop you from stress eating
He recommends letting frozen grapes melt in your mouth. “The cold temperature activates TRPM8 receptors in the mouth, which ...
Nature5y
Activation of the TRPM8 channel can generate analgesia in chronic neuropathic pain
Peripheral or central activation of the TRPM8 (transient receptor potential melastatine family member 8) cool-sensitive ion channel can produce an analgesic effect, reversing hypersensitivity and ...
Nature5y
Icilin proves a powerful soother of pain
Researchers at the University of Edinburgh (Scotland) set out to test whether TRPM8, a 'cool-sensitive' transient receptor potential cation channel, is involved in the pain-relief mediation of ...