Scientists discover how TGF-Beta sends its message even while tethered to the cell membrane
Knowing that TGF-Beta was capable of unlocking its receptor while bound by LAP, the UCSF scientists suspected that these ...
Medscape3y
Evolving Concepts of Liver Fibrogenesis Provide New Diagnostic and Therapeutic Options
They offer innovative diagnostic and therapeutic options. As an example, modulation of TGF-β/BMP-7 ratio changes the rate of EMT, and so the simultaneous determination of these parameters and of ...
eLife3d
Spatial confinement induces reciprocating migration of epidermal keratinocytes and forms triphasic epithelia
In this manuscript the authors established a novel three-dimensional culture system for stratified epithelia that allows epithelial cells to undergo epithelial-to-mesenchymal transition (EMT) and ...