More information: Hao Zeng et al, Modular alkene synthesis from carboxylic acids, alcohols and alkanes via integrated ...

Herein, the authors report a divergent alkynylative difunctionalization of amides in a single transformation to generate either amines or alcohols through C–O or C–N cleavage. Synthesis of ...

Yu's lab has already pioneered methods to unlock similar bonds in acids, alcohols and amines, three other major chemical groups critical to drug synthesis. The new method with ketones—and to an ...

Optically pure alcohols are prevalent motifs in natural products and pharmaceuticals, driving the development of effective methods for their synthesis. Since the first reports of the Kharasch ...