Study participants were randomly assigned to receive subcutaneous semaglutide 7.2mg, semaglutide 2.4mg, or placebo once weekly; all treatments were in conjunction with lifestyle interventions.
The company states: “Novo Nordisk (NVO) announced headline results from STEP UP, a phase 3b trial in the global STEP programme. STEP UP is a 72-week efficacy and safety trial investigating ...
TAMPA BAY, Fla. (BLOOM) – If you’ve recently stopped taking semaglutide—commonly known by brand names like Ozempic or Wegovy—you may be wondering how to transition back to normal while ...
The topline results from the ESSENCE trial of semaglutide showed that a once-weekly 2.4mg dose of the drug was better than placebo at resolving MASH and improving liver fibrosis, meeting its ...
The phase 3b STEP UP trial has been comparing the experimental 7.2mg dose of semaglutide to the standard 2.4mg dose of the drug and placebo, all given once weekly in conjunction with lifestyle ...
In addition, 33.2% of those who received semaglutide 7.2 mg achieved a weight loss of 25% or more after 72 weeks, compared to 16.7% with semaglutide 2.4 mg and 0.0% with placebo.