When activated acutely, the UPR is an adaptive response; it slows the synthesis of new proteins, reducing the protein folding load and alters many molecular and metabolic processes within the cell to ...

Protein folding is the process by which proteins achieve their mature functional (native) tertiary structure, and often begins co-translationally. Protein folding requires chaperones and often ...

Control of protein folding and mis-folding in vivo: recognition of unfolded protein, the UPR or unfolded protein response, proteostasis, and the role of the ubiquitin-proteasome system.

Already a Honolulu Star-Advertiser subscriber? Log in now to continue reading. Moreover, protein folding doesn’t happen in isolation. Inside cells there are specialized molecules called ...

They identify how altered protein folding drives multicellular evolution. In a new study led by researchers from the University of Helsinki and the Georgia Institute of Technology, scientists ...

Control of protein folding and mis-folding in vivo: recognition of unfolded protein, the UPR or unfolded protein response, proteostasis, and the role of the ubiquitin-proteasome system.