Progressive supranuclear palsy (PSP) is a rare neurodegenerative condition that is a form of atypical parkinsonism ... some patients exhibit the “round the houses” sign on neuro-ophthalmologic ...

The levels of neurofilament light chain in the cerebrospinal fluid of people with progressive supranuclear palsy were found to be higher than those of people with Alzheimer's disease (effect size = ...

Historically, frontotemporal lobar degeneration (FTLD), corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP ... often a precursor of these conditions. Early descriptions ...

Progressive supranuclear palsy (PSP) and corticobasal degeneration ... PSP diagnostic criteria are very specific in diagnosing this disease, whereas CBD criteria need to be refined and validated.

More information: Miriam Scarpa et al, Post mortem validation and mechanistic study of UCB‐J in progressive supranuclear palsy patients' brains, Alzheimer's & Dementia (2024). DOI: 10.1002/alz.14409 ...

progressive supranuclear palsy) and motor neurone disease. The finding of neurologic signs in addition to cognitive impairments in the mild and moderate stages of dementia suggests a diagnosis ...

Inflammatory Trigger a New Clue in Alzheimer's Jan. 6, 2023 — Researchers have identified a new trigger of brain inflammation in Alzheimer's disease and progressive supranuclear palsy ...

and cerebral cortex of patients with progressive supranuclear palsy (PSP). This group has now shown that a low ratio of these tau forms reliably differentiates patients with PSP from controls and ...

which has more parkinsonian symptoms but is relatively unresponsive to the usual therapy for Parkinson’s disease (i.e., levodopa). Some of the atypical parkinsonian disorders, such as progressive ...

A Longframlington man completed ‘Britain’s most brutal race’ to raise awareness of a rare terminal condition following his ...