A recent study identified that a special group of pancreatic beta cells are crucial for triggering the blood sugar response. We know that beta cells of the pancreas play an important role in ...

In this type of diabetes, the immune system specifically destroys insulin-secreting beta cells in the pancreatic islets — the body's own immune system attacks its own cells (a form of autoimmune ...

Our perspective about glucose toxicity as it pertains to the pancreatic ß-cell is that the characteristic decreases in insulin synthesis and secretion are caused by decreased insulin gene expression.

When they looked at pancreas tissues from people with recent-onset T1D, they found that the beta-cell function was within the ...

Increased levels of glucose in the circulation lead to increased glucose uptake into pancreatic beta cells through GLUT2, a glucose transporter. Increased intracellular glucose then leads to ...