The beads are called nucleosomes. Each nucleosome is made of DNA wrapped around eight histone proteins that function like a spool and are called a histone octamer. Each histone octamer is composed ...

Each nucleosome is composed of a little less than two turns of DNA wrapped around a set of eight proteins called histones, which are known as a histone octamer. Each histone octamer is composed of ...

The DNA (red) is wound around two sets of core histone proteins (green) to form a kind of bead on a string. The H1 histone protein clamps the DNA into place where it enters and exits a bead.

In fact, one effect of DNA methylation can be to recruit proteins to mediate histone modification 1. Figure 2 | Nucleosomes and histone tail modifications. A) A nucleosome consists of DNA associated ...

in this case histone 4 (H4), one of the nucleosome core forming histones. After purifying the chromatin fragments from the formaldehyde-fixed cells, the team immunoprecipitated the DNA-protein ...

Now, Warnecke and colleagues are challenging the idea that these space-saving proteins are not commonplace in bacteria. In a preprint uploaded to bioRxiv this January that has yet to undergo peer ...

Specific proteins (histones) wind up the DNA like small cable drums to package the long DNA. A cable drum (consisting of four pairs of histones) with coiled DNA is called a nucleosome and is the ...

Histone deacetylase inhibitors (HDACi) are a new class of antineoplastic agents with demonstrable preclinical antitumor activity in both in vitro and in vivo studies in a wide range of ...

Approximately 50% of chromosomes and chromatin is protein. These include histones, transcription factors, nuclear receptors, co-activators, co-repressors, histone modifying enzymes, nucleosome binding ...

Over 20 distinct proteins and protein complexes ... of the checkpoint signaling cascade using biochemical and structural approaches. Nucleosome positions and histone modifications are critical ...

The DNA of eukaryotes is compacted as chromatin, with the nucleosome representing a basic ... restricts the accessibility for DNA-binding proteins such as transcription factors.