They then inserted mouse follicles—balls of hormone-secreting cells encasing ... The researchers then inserted follicle-seeded, printed ovaries into seven female mice whose natural ovaries they had ...

FOXL2 and USP7 share some common roles in humans. People lacking one copy of the FOXL2 gene can start making eggs but don't ...

Earlier attempts to make a bi-paternal mouse used ovarian organoids to derive oocytes from male pluripotent stem cells; those oocytes were then fertilized with sperm from another male. However, when ...

Researchers created the first bi-paternal mouse by modifying imprinting genes, advancing reproductive science but facing ...

A team of scientists created a bi-paternal mouse through targeted imprinting gene edits in embryonic stem cells. This demonstrates the potential for overcoming barriers to unisexual mammalian ...

Earlier attempts using ovarian organoids have failed to produce a viable bi-paternal mouse due to abnormalities in the imprinting genes.

Stem cell scientists have successfully used embryonic stem cell engineering to create a bi-paternal mouse — a mouse with two ...

During this project, the researchers took a mouse monoclonal antibody called 10D7 that binds strongly to CDCP-1, a protein that’s abundant on the surface of ovarian cancer cells, and they ...