The Finley Lab investigates how cellular metabolic pathways regulate cell fate decisions in stem cells and cancer cells. We combine genetic and metabolomic approaches to investigate cell-type specific ...

Cell Metabolism, launched in January 2005 ... with an emphasis on understanding the molecular basis of how the body self-regulates in the face of change, and how disturbances in these balances ...

The cell can control a metabolic pathway by the presence or absence of a particular enzyme. The cell can also regulate the rate of reaction of key enzymes. Enzymes are able to bind to their ...

Metabolism refers to all of the chemical reactions that take place inside living cells. Unicellular and multicellular ... their metabolism. Both must regulate their temperature to maintain optimum ...

A recent Science study explored how intranuclear metabolic enzymes establish the link between locus-specific epigenetic reprogramming of T cells and nutrient availability. Persistent antigen ...

Antibiotics are a double-edged sword—they should be as toxic as possible to pathogenic bacteria while being harmless to the cells ... MEP pathway is an essential part of the energy metabolism ...

Indeed, in most cases the fate ... pathways the researchers investigated, just 14 were responsible for 80% of the metabolic impact of autism. The pathways that were most changed are related to the ...

However, how birth-associated metabolic changes affect the fate of tissue stem ... Considering that glutamine metabolism also regulates the functions of tissue stem cells other than NSCs, our ...

A research group led by Kazunobu Sawamoto, a professor at Nagoya City University and National Institute for Physiological Sciences, and Koya Kawase, a pediatric doctor at Nagoya City University ...

The results highlight an important physiological function of PGAM in the differentiation and suppressive activity of Treg cells by regulating serine synthesis. This role is proposed to intersect with ...