More recently, in a metastatic mouse melanoma model, B 16 /F 10, we have observed elimination of the lung metastases, when the targeted wt p53 liposomes were systemically delivered in combination ...

One such mechanism involves a protein called p53. Often dubbed the "guardian of the genome," this protein plays a pivotal role in ensuring that your cells grow, divide and die in an orderly fashion.

The stem cell signal Msi2 plays a dual role in lung cancer, acting as a signal that is not only essential for initiation, but also for propagation of the tumor.

New Drug Research & Development Co. Ltd. has disclosed cellular tumor antigen p53 (TP53) (Y220C mutant) stabilizers reported to be useful for the treatment of cancer.

Type 1 dendritic cells are key to initiate and maintain anti-tumoral T-cell responses in diverse tumour tissues. Our lab focuses on tissue-specific properties of cDC1 in lung tumours, focusing on the ...