Sciatica is a common cause of buttock pain that occurs when the sciatic nerve gets compressed or pinched. It causes nerve pain that starts in the spine at the lower back and goes into the buttocks ...

What Is SI Joint Pain? Injury, pregnancy, or uneven movement in your pelvis can cause low back, butt, and leg pain ... some of the biggest joints in your body because they're where your spine ...

They run from your lower back down through your butt and into each leg (see the graphic, below). Your pain could be felt on either side of the body and, furthermore, is often misdiagnosed, says Dulak.