“The characteristic fluorescent signatures are thought to be the result of an accumulation of lipofuscin in the retina,” explained Petrich and his team. Lipofuscin is pigmented waste material ...

The disease is characterized by changes in the retinal pigment epithelium (RPE ... of harmful substances in the RPE, such as lipofuscin and drusen deposits, which are associated with the ...

People with Stargardt disease have too much lipofuscin -- it builds up over the macula, which is the central part of the retina and is responsible for clear and sharp central vision. Stargardt ...