The chain of nucleosomes is then wrapped into a 30 nm spiral called a solenoid, where additional H1 histone proteins are associated with each nucleosome to maintain the chromosome structure.

With this strategy, he discovered over 400 bacterial proteins that contain a signature 3D histone structure called a histone fold, suggesting histones could be scattered across many bacterial species.

Berger and her collaborators chemically altered histone structure in the brains of young majors using small-molecule inhibitors of histone deacetylases or small interfering RNAs (siRNAs). Newly ...

How? Scientists are using ChIP and PCR to find out. To examine changes in histone modification during blood cell development in chickens, the investigators started with whole chromatin from ...