This enzyme is able to silence specific DNA sections by epigenetically modifying histone proteins that package the DNA. These modifications ensure that the DNA is densely packed as heterochromatin ...

Histone modification can open chromatin ... Likewise, demethylated DNA does not draw deacetylating enzymes to the histones, but it often attracts histone acetyltransferases, allowing histones ...

The following is a summary of “Histone Modifications and DNA Methylation in Psoriasis: A Cellular Perspective,” published in the January 2025 issue of Allergy and Immunology by Pan et al. Epigenetic ...

After they are incorporated into DNA, the drugs block DNMT enzymes from acting, which inhibits DNA methylation. Drugs aimed at histone modifications are called histone deacetylase (HDAC ...

By uncovering how these histone modifications influence the brain ... The lab further learned that the enzyme responsible for modifying histones with serotonin and dopamine is transglutaminase ...

and exchanger” given that the addition and removal of other histone modifications, including methylation, are carried out by different enzymes. Maze says the exchange of neurotransmitters on ...

Epigenetic modifiers, enzymes that catalyze covalent modifications on chromatin ... into the catalytic and noncatalytic functions of the histone methyltransferase SETD2, a protein responsible ...

The SCAN enzyme is at the heart of this discovery ... in metabolic and signaling functions, including histone acetylation and protein modification. However, its role in NO transport via SNO ...

The research could contribute to the development of more effective anti-aging treatments in the future. The body's aging ...

The lab further learned that the enzyme responsible for modifying ... "This unique mechanism suggests that additional histone monoamine modifications could be dynamically regulated, potentially ...