Vaginal creams are medicines inserted into the vagina to treat a bacterial or fungal infection or to deliver estrogen to people with vaginal atrophy (thinning). It is important to apply the cream ...

You may opt to apply estrogen topically with a cream, gel, or spray. This option is less likely to cause blood clots, but make sure that you keep estrogen cream out of reach from anyone else in ...

Prescription estrogen creams are intended for vaginal use ... even less estrogen would make it into the blood through facial application, said Elizabeth Suh-Burgmann, chair of gynecologic oncology ...