In 2021, the American College of Chest Physicians released clinical guidelines that suggested reduced dosage of either apixaban or rivaroxaban for extended management of blood clots, noting this ...

Purpose The pharmacology, pharmacokinetics, efficacy, and safety of apixaban are reviewed ... and has been administered in a twice-daily dosing regimen in clinical trials without the need for ...

DOACs, such as rivaroxaban (brand name Xarelto) and apixaban (brand name Eliquis ... At hospitals across Michigan, off-label dosing of DOACs was relatively common among patients being treated ...