Mild (CrCl 60-89 mL/min) or moderate (CrCl 30-59 mL/min) renal impairment: reduce the Effexor XR total daily dose by 25% to 50%. Severe renal impairment (CrCl <30 mL/min) or patients undergoing ...

Your healthcare provider may recommend gradual dose increases if needed. Effexor XR Starting dose: 75 mg daily, although some people will start at 37.5 mg daily for the first week before ...

and dosing regimens. Cymbalta and Effexor XR are selective serotonin and norepinephrine reuptake inhibitors (SNRIs). They work to increase the amounts of serotonin and norepinephrine in the brain ...